Targeted inactivation of the fish aromatase gene

Major Goals and Objectives

  • Initiate embryonic stem (ES) cell cultures derived from zebra fish embryos and maintain the cultures for multiple passages in vitro
  • Construct targeting vectors that can be used to disrupt the zebra fish aromatase genes
  • Introduce the targeting vectors into the ES cells and develop methods to isolate homologous recombinants
  • Use the ES cell cultures to generate zebra fish aromatase knockout
    lines of fish

Research Information

Principal Investigator:
Paul Collodi
Initiation Date:
Completion Date:
Purdue University

Our Work


Paul Collodi
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